Aminophylline and propofol: apparent antagonism
نویسندگان
چکیده
منابع مشابه
the effect of aminophylline on hemodynamic parameters and recovery time after propofol infusion
abstract aim and background: this study is aimed to assess the effect of aminophylline (1mg/kg) on reversal of the sedative effects of propofol and the recovery time in patients under propofol anesthesia. due to the known effects of aminophylline on myocardial contractility and the increase in cardiac output, its effects on hemodynamic changes of propofol are also assessed. methods and materi...
متن کاملTRPA1 and TRPV1 contribute to propofol-mediated antagonism of U46619-induced constriction in murine coronary arteries
BACKGROUND Transient receptor potential (TRP) ion channels have emerged as key components contributing to vasoreactivity. Propofol, an anesthetic is associated with adverse side effects including hypotension and acute pain upon infusion. Our objective was to determine the extent to which TRPA1 and/or TRPV1 ion channels are involved in mediating propofol-induced vasorelaxation of mouse coronary ...
متن کاملPropofol and Aminophylline Antagonize Each Other During the Mobilization of Intracellular Calcium in Human Umbilical Vein Endothelial Cells
This study examined whether propofol and aminophylline affect the mobilization of intracellular calcium in human umbilical vein endothelial cells. Intracellular calcium was measured using laser scanning confocal microscopy. Cultured and serum-starved cells on round coverslips were incubated with propofol or aminophylline for 30 min, and then stimulated with lysophosphatidic acid, propofol and a...
متن کاملThe effect of aminophylline on loss of consciousness, bispectral index, propofol requirement, and minimum alveolar concentration of desflurane in volunteers.
BACKGROUND Adenosine is a soporific neuromodulator; aminophylline, which is clinically used as a bronchodilator, antagonizes the action of adenosine in the central nervous system. Thus, we tested the hypothesis that aminophylline delays loss of consciousness (LOC) and speeds recovery of consciousness (ROC) with propofol anesthesia, and that aminophylline increases the minimum alveolar concentra...
متن کاملتعیین اثر آمینوفیلین بر تغییرات همودینامیک و زمان ریکاوری بعد ازبیهوشی با پروپوفول
Abstract Aim and Background: This study is aimed to assess the effect of aminophylline (1mg/kg) on reversal of the sedative effects of propofol and the recovery time in patients under propofol anesthesia. Due to the known effects of aminophylline on myocardial contractility and the increase in cardiac outpu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Anaesthesia
سال: 1988
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.1988.tb06647.x